Claims it “can help you maintain good hearing health” and “tinnitus and poor connection between the brain and the eardrum are all eliminated".

Version: July 2023 Last updated: August 2023 To be reviewed: July 2026

Treatment details

Illustration of a bottle with a star on the front of it.


Branded dietary supplement



Evidence of harm



Evidence that it is not effective



Claims for Cortexi

Cortexi will “can help you maintain good hearing health” and “tinnitus and poor connection between the brain and the eardrum are all eliminated” [1]

What is the treatment?

It is unclear. One site calls them “ear drops” and discusses moistening the ear drum and minimising the accumulation of ear wax[1] whereas other sites say that it is a liquid to be swallowed once or twice a day[2,3]. The supplement claims to contain[1-3] : Grapeseed extract; green tea leaf extract; annual
cayenne; Chinese ginseng; astragalus; chromium picolate; maca root; gymnema sylvestre.

What are the downsides of this treatment?

Potential side effects from constituents.[4-6]

Cost – this supplement currently is on sale for $69.00 for one month’s supply excluding shipping.[2]

Has there been research into this treatment?

There have been no papers published on Cortexi as a supplement, but there have been a number published on its component parts. Some of these relate to tinnitus.

What does the research say?

There is limited evidence that ginseng in doses of 3,000mg per day may reduce Tinnitus Handicap Inventory (THI) scores[7]. There is no evidence that any of the other components of this supplement
are effective for treating tinnitus[4,6,8-13] . Although some of the components are thought of as safe, chromium can interact negatively with other medication you may be taking2 and green tea extract can be harmful in large doses[4 7 8].

Although independent evidence is limited, what there is does not show that the components of this supplement are effective for tinnitus and that there may be risks involved in taking this supplement. We would suggest you talk to
your GP before taking any new medication or supplement. “Dietary supplements should not be recommended to treat tinnitus.”[14]

Tinnitus UK


The seller’s website states that “Statements on this website have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure or prevent any disease.”[2]

All online references accessed 11 July 2023 unless noted.

1. Mid-day. Cortexi Reviews.

2. Cortexi Research. Claim Your Discounted Cortexi Below While Stock Lasts.

3. Journal of Public Health Research. Cortexi Reviews.

4. The Drugsite Trust. Green tea.

5. Hu J, Webster D et al. The Safety of Green Tea and Green Tea Extract Consumption in Adults – Results of a Systematic Review. Regulatory Toxicology and Pharmacology. (2018) 95. 412-433. DOI: 10.1016/j.yrtph.2018.03.019

6. The Drugsite Trust. Ginseng.

7. Liu D, Hu Y, Wang D, Han H, Wang Y, Wang X, Zhohu Z, Ma Y, Dong Y. Herbal Medicines in the treatment of tinnitus: An updated review. Frontiers in Pharmacology. Volume 13 – 2022. DOI:

8. The Drugsite Trust. Grape Seed.

9. The Drugsite Trust.Capsicum Peppers. peppers.html

10. The Drugsite Trust.Astragalus.

11. National Institutes of Health Office of Dietary Supplements. Chromium. www.

12. The Drugsite Trust. Maca.

13. The Drugsite Trust. Gymnema.

14. Coelho C, Tyler R et al. Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus. American Journal of Audiology. (2016) 25(3): 184-205